Danny was born in born April 1,In Birmingham, Alabama, the son u of John (Hoffman). He graduated from Thomas Jefferson High School in 1979.

He completed an Associate’s degree in paramedic technology at John Hopkins University in 1981, followed by a Bachelor of Arts in kinesiology and exercise physiology from The University of Texas, and a Master of Science in genetics from The University of Texas-Permian Basin in 1986. He received his M.D. in 1990 from the University of Texas Medical Branch in Galveston, Texas, and completed his residency in emergency medicine at Scott and White Hospital in Temple, Texas,where he was chief resident from 1996-1997. In 2002, he obtained his Master of Public Health and completed an aerospace medicine fellowship at The University of Texas Medical Branch (UTMB), Galveston. In 1994, he completed an externship with the “Royal Flying Doctor Service” and “The Australian Rural Health Service” in Yuendumu Aboriginal Nation, Northern Territory, Alice Springs. After his residency, he returned to Birmingham, Alabama, and practiced emergency medicine at Brookwood medical center. In 1997, he became an FAA medical examiner practicing from his family ranch in Alabama. He married Sonya Jones on June 20, 2005 and have a lovely daughter ' Cambrie'. His Medical career, he was a clinical assistant professor in Preventive Medicine and Community Health at University of Texas Medical Branch. He was also a preceptor at Texas A&M; Health Science Center from 2006 to 2007 and then as an assistant professor in 2008-2010.

He is on the Advisory Council for the University of Texas Permian Basin. From October 2011 till present, Danny served as Medical Officer/expeditionary physician for National Science Foundation South Pole Station supporting station personnel and summer expeditionary away teams in the Trans Antarctic range, and was medical support during the race around the world and South Pole marathon events. As of 2013, Danny works for Emergency Service Partners, L.P. in College Station, Texas. NASA career Danny was selected to the UTMB aerospace medicine residency in conjunction with NASA in 2000. During his time he spent three years at the Yuri Gagarin Cosmonaut Training Center in Star City, Russia. He was selected as deputy crew surgeon for Expedition. In 2010 when the International Space Station ran low on food supplies, Danny oversaw the calories