acannabis dispensary

In the brain, there are specific receptors for several endogenous substances, that is, that the body itself produces. Many drugs act on these receptors, helping them to pick up these substances or blocking them so that they do not pick up substances that can cause problems.

One of the types of receptors are cannabinoid receptors. They are known as CB1 and CB2. THC is one of the substances that has an affinity for these receptors and activates them. The “cheap” effect is due to the activation of CB1 by THC.

Unlike THC, CBD has little affinity for the cannabinoid receptors in the brain, but is an antagonist of them. This means that when it binds to these receptors, it occupies the space without activating them, preventing them from being activated by substances with affinity.

Because of this, one of the effects of cannabis dispensary is a reduction in the effect of THC. However, the difference is small, since, when occupying CB2 receptors, the concentration of THC in CB1 receptors is higher.

It can also bind to other receptors, such as 5-HT1A - a serotonin receptor -, which influences mood and is strongly related to depression. This connection may be related to the antidepressant, anxiolytic and neuroprotective effects of CBD.