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Ambien is a sleeping drug, which also has an anxiolytic, anticonvulsant, sedative and myorelaxant effect. Ambien contains zolpidem– a drug substance that falls within the group of cyclopyrrolones similar to benzodiazepine derivatives.
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The action of Ambien is implemented by specific stimulation of GABA receptors.
The use of zolpidem leads to an increased duration of sleep, reduced frequency of night and early awakenings, as well as a sleep quality improvement. During the research, zopiclone reduced the time of the I stage of sleep, extended the II stage of sleep and increased or maintained the period of deep sleep and maintained paradoxical sleep.
Mode of application
Ambien is taken orally directly before sleep. In the beginning of treatment, the patient is prescribed a minimum dose, which is later titrated. During the therapy, it is recommended to use the lowest dose, which gives the desired effect. If there is no improvement in the patient’s condition within a few days of treatment, the diagnosis should be reconsidered (insomnia can be the result of a number of mental and physical diseases).
Average recommended doses of Ambien
Adult people need to take 1 pill of Ambien before sleep.
Persons over the age of 65 should be prescribed 1/2 pill of Ambien before sleep (the dosage of 1 pill should be used only in exceptional cases).
Patients of special groups (liver, kidney and respiratory failure) should take 1/2 pill of Ambien before sleep.
Duration of course
Usually, the short-term use of Ambien is recommended (no more than 28 days, including the cancellation period of zolpidem). Ambien pills should be withdrawn by gradually decreasing the dose of zolpidem.
For situational insomnia, a course of 2-5 days is recommended, while the patients with temporary insomnia should take the drug for 2-3 weeks.
A longer treatment can be recommended in rare cases (after a thorough diagnosis and under constant supervision of the specialist). The long-term use of benzodiazepines and their derivatives can lead to reduced effectiveness of conventional doses (patients who used zopiclone for less than 28 days didn’t observe a significant decrease in effectiveness).