David Tham founded nanoKnowledge in Singapore (2003) and Australia (2006). His career spans international publishing and broadcast media companies, the Asia-Pacific IT & telecommunications sector, and the global travel & lodging industry, including hands-on entrepreneurial experience managing start-up businesses and innovative ventures. David is noted for his pioneering work in Internet enterprise, e-learning innovation and social media marketing communications since 1996.

David began his career in broadcast and print journalism in Singapore in 1996. In 2000-2001, he worked as the creative director of GetIT Multimedia, a Silicon-Valley-headquartered dot-com company specialising in rich-media-applications and e-learning in the Asia Pacific. Since then, David has held key management and senior consulting positions in award-winning multinational private corporations and the public service.

As the chief knowledge officer of the Raffles International hotels & resorts group in 2001-2003, David facilitated the knowledge capital integration of the newly-acquired Swissôtel and Resorts chain with the Raffles Hotels and Resorts. His efforts led the corporate group to win the Intelligent Enterprise 20 Award (2002). Appointed as Senior Consultant to the Singapore Workforce Development Agency (WDA) and Ministry of Manpower (MOM) in 2004-2005, David facilitated national workplace strategy development for industry and promoting workplace leadership in the Tourism and Hospitality, Healthcare, Retail, Aerospace (MRO) and Logistics (Services) industry sectors respectively.

Over the years, David has influenced a combined total of more than SGD$2.5 million worth of funding across a variety of private and/or social enterprise projects in Singapore and internationally. For these and other achievements, Global Knowledge Review (UK) described David as "one of Asia's preferred strategists for implementing human capital and knowledge management initiatives" (2004 and 2005). In 2016, David's story of entrepreneurship was chosen by Curtin School of Management as a case study to teach Curtin University students about Opportunity Recognition (MGMT3004 Entrepreneurship).

An award-winning scholar and alumnus of the John Curtin Institute of Public Policy (JCIPP) at Curtin Business School, Australia, David is a published author and conference presenter on the applications of the Internet and social media audiences to businesses and industries.