Jamie Mark

Pseudoindoxyl and 7-hydroxymitragynine (7OH) are two of kratom’s most potent alkaloids, typically found in concentrated extracts rather than raw leaf. 7OH is known for its rapid onset and strong, intense effects, while pseudoindoxyl provides a smoother, longer-lasting experience. The key difference between them lies in receptor interaction, with pseudoindoxyl acting more selectively. Both compounds are significantly stronger than standard kratom alkaloids and should be used cautiously and responsibly.