Moderna Therapeutics

Moderna Therapeutics is a privately-held biotechnology company based in Cambridge, Massachusetts, founded based on pioneering discoveries made at the Children’s Hospital of Boston and Massachusetts Institute of Technology.

The company is pioneering messenger RNA therapeutics™, a revolutionary new method of producing proteins in vivo to treat a variety of serious diseases. Messenger RNA therapeutics™ stimulate the production of human proteins or antibodies inside patient cells, which are in turn active intracellularly or secreted into the bloodstream to become active in other areas of the body. This breakthrough platform addresses currently undruggable targets and offers a superior alternative to existing drug modalities for a wide range of disease conditions. If successful in human clinical trials, Moderna Therapeutics’ messenger RNA technology will usher in the first entirely new way of making therapeutic proteins since the development of recombinant technology more than 30 years ago, with dramatic implications for both patients and industry. Moderna Therapeutics has conducted proof-of-concept studies in multiple preclinical models, and a manuscript describing the success of our approach in inducing in vivo protein production appeared in Nature Biotechnology. Learn more about the revolutionary science behind Moderna Therapeutics.

Moderna Therapeutics has established preclinical programs in four key therapeutic areas where high unmet patient needs require new approaches: oncology supportive care, inherited genetic disorders, hemophilia, and diabetes. Moderna Therapeutics plans to develop and commercialize its innovative messenger RNA therapeutics™—initially for rare diseases and oncology—and will seek partnerships in other disease areas to ensure our groundbreaking approach is rapidly translated into new treatments for patients in need.

Moderna Therapeutics is led by a team of seasoned biotechnology executives and scientific and business advisors with experience developing and commercializing innovative medicines, and has attracted an exceptional team of scientists and staff to bring its vision to life. Learn more about the executive leadership at Moderna Therapeutics.

Privately-held Moderna was founded in late 2010 by Flagship VentureLabs, and currently has strategic agreements with As