Alejandro Speck Planche

My current research is devoted to the construction of multi-tasking models for quantitative-structure biological effect relationships (mtk-QSBER). These models represent evolutive stages of the classical QSAR models, allowing the integration of different kinds of chemical and biological data.

For instance, in drug discovery, it is possible to use a single unified mtk-QSBER model as efficient chemoinformatic tool to perform virtual screening of large libraries/databases of molecules. One single mtk-QSBER model can realize predictions from preeliminar in vitro tests against biomolecular targets, passing through predictions involving cell lines and microorganisms, to the assessment of parameters assoiciated with preclinical studies and clinical trials.