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Forxiga (dapagliflozin) works by targeting a specific mechanism in the kidneys to help lower blood sugar levels in individuals with type 2 diabetes. Here's how it works:
Kidney Glucose Reabsorption: Normally, the kidneys play a crucial role in filtering the blood to remove waste products and excess substances. One of these substances is glucose (sugar). In healthy individuals, the kidneys filter glucose from the blood but then reabsorb most of it back into the bloodstream to prevent its loss through urine.
Inhibition of SGLT2: Forxiga is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. SGLT2 is a protein found in the kidneys that is responsible for reabsorbing glucose back into the bloodstream. Forxiga works by inhibiting the action of SGLT2, which reduces the ability of the kidneys to reabsorb glucose.
Increased Glucose Excretion: By inhibiting SGLT2, Forxiga allows more glucose to remain in the urine. This results in an increased excretion of glucose through urine, which leads to lower blood sugar levels in individuals with type 2 diabetes.Forxiga 10 mg tablets price uk are affordable.